Powder: -20°C for 3 years | In solvent: -80°C for 1 year
7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties and can be used in the study of neuropathic pain.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 265.00 | |
5 mg | In stock | $ 657.00 | |
10 mg | In stock | $ 935.00 | |
25 mg | In stock | $ 1,380.00 | |
50 mg | In stock | $ 1,890.00 | |
100 mg | In stock | $ 2,980.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 397.00 |
Description | 7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties and can be used in the study of neuropathic pain. |
Targets&IC50 | PTPRD:1-3 μM (Human), PTPRS:40 μM (Human) |
In vitro | 7-BIA inhibits recombinant human PTPRD and recombinant human PTPRS with IC50 values of approximately 1-3 μM and 40 μM, respectively[1]. |
In vivo | Administered via intraperitoneal injection at a single dose of 10-20 mg/kg, 7-BIA reduces cocaine self-administration in experienced wild-type mice[1]. |
Animal Research | Animal Model: WT mice (available cocaine 50 times, 1 mg/kg infusions on FR1 schedule during ≥20 prior sessions). Dosage: 10 mg/kg, 20 mg/kg. Administration: Given i.p.; only once |
Molecular Weight | 294.3 |
Formula | C15H18O6 |
CAS No. | 1313403-49-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 80 mg/mL (271.83 mM), Sonication is recommended.
Ethanol: 30 mg/mL (101.94 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
7-BIA 1313403-49-4 Metabolism Phosphatase 7 BIA 7BIA inhibitor inhibit