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7-BIA
Catalog No. T10190Cas No. 1313403-49-4
7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research.
7-BIA
Catalog No. T10190Cas No. 1313403-49-4
7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $148 | In Stock | |
| 5 mg | $372 | In Stock | |
| 10 mg | $645 | In Stock | |
| 25 mg | $1,190 | In Stock | |
| 50 mg | $1,880 | In Stock | |
| 100 mg | $2,980 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $397 | In Stock |
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | 7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties, and is utilized in neuropathic pain research. |
| Targets&IC50 | PTPRD:1-3 μM (Human), PTPRS:40 μM (Human) |
| In vitro | 7-BIA inhibits recombinant human PTPRD and recombinant human PTPRS with IC50 values of approximately 1-3 μM and 40 μM, respectively[1]. |
| In vivo | Administered via intraperitoneal injection at a single dose of 10-20 mg/kg, 7-BIA reduces cocaine self-administration in experienced wild-type mice[1]. |
| Animal Research | Animal Model: WT mice (available cocaine 50 times, 1 mg/kg infusions on FR1 schedule during ≥20 prior sessions). Dosage: 10 mg/kg, 20 mg/kg. Administration: Given i.p.; only once |
| Molecular Weight | 294.3 |
| Formula | C15H18O6 |
| Cas No. | 1313403-49-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (271.83 mM), Sonication is recommended. Ethanol: 30 mg/mL (101.94 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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