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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $148 | In Stock | |
5 mg | $372 | In Stock | |
10 mg | $645 | In Stock | |
25 mg | $1,190 | In Stock | |
50 mg | $1,880 | In Stock | |
100 mg | $2,980 | In Stock | |
1 mL x 10 mM (in DMSO) | $397 | In Stock |
Description | 7-BIA is a receptor-type protein tyrosine phosphatase D (PTPRD) inhibitor with anti-addictive properties and can be used in the study of neuropathic pain. |
In vitro | 7-BIA inhibits recombinant human PTPRD and recombinant human PTPRS with IC50 values of approximately 1-3 μM and 40 μM, respectively[1]. |
In vivo | Administered via intraperitoneal injection at a single dose of 10-20 mg/kg, 7-BIA reduces cocaine self-administration in experienced wild-type mice[1]. |
Animal Research | Animal Model: WT mice (available cocaine 50 times, 1 mg/kg infusions on FR1 schedule during ≥20 prior sessions). Dosage: 10 mg/kg, 20 mg/kg. Administration: Given i.p.; only once |
Molecular Weight | 294.3 |
Formula | C15H18O6 |
Cas No. | 1313403-49-4 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 80 mg/mL (271.83 mM) Ethanol: 30 mg/mL (101.94 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO/Ethanol
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