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7-O-Methylaloeresin A
Catalog No. TN1332Cas No. 329361-25-3
7-O-Methylaloeresin A shows significant antioxidant activity, it also has moderate inhibitory active on BACE.
7-O-Methylaloeresin A
Catalog No. TN1332Cas No. 329361-25-3
7-O-Methylaloeresin A shows significant antioxidant activity, it also has moderate inhibitory active on BACE.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | $290 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $440 | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | 7-O-Methylaloeresin A shows significant antioxidant activity, it also has moderate inhibitory active on BACE. |
| In vitro | The latex and its two constituents were assessed for their possible antimicrobial activities against 23 bacterial and four fungal strains using the disc diffusion method and their antioxidant activity by two complementary test systems, namely 2,2-diphenyl-1-picrylhydrazyl (DPPH) and 2-deoxyribose degradation assay methods. The isolated compounds showed promising results against various pathogenic bacterial and fungal strains in comparison with standard drugs. Moreover, 7-O-Methylaloeresin A exhibited good activity against multiple drug resistant Staphylococcus aureus (NCTC 11994) and Salmonella typhimurium (ATCC 1255) with MIC values of 0.72 and 0.18 mm, respectively. Among the fungal strains tested, Candida albicans (ATCC 10231) was the most susceptible organism to the latex and the two isolated compounds. The latex and isolated compounds also showed significant activities on both antioxidant assays with the highest activity being observed for 7-O-Methylaloeresin A, which gave IC(50) values of 0.026 mm and 0.021 mm for DPPH and 2-deoxyribose degradation assay, respectively. |
| Molecular Weight | 554.54 |
| Formula | C29H30O11 |
| Cas No. | 329361-25-3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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