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7 Beta-Hydroxycholesterol

🥰Excellent
Catalog No. TN1338Cas No. 566-27-8
Alias 7β-Hydroxycholesterol

7 Beta-Hydroxycholesterol (7β-Hydroxycholesterol) is an oxysterol contained in animal-derived foods. It is an oxidative stress inducer and a candidate marker for assessing cardiovascular risk factors in obesity. It can induce oxidative stress and inflammation and promote atherosclerosis.

7 Beta-Hydroxycholesterol

7 Beta-Hydroxycholesterol

🥰Excellent
Purity: 99.24%
Catalog No. TN1338Alias 7β-HydroxycholesterolCas No. 566-27-8
7 Beta-Hydroxycholesterol (7β-Hydroxycholesterol) is an oxysterol contained in animal-derived foods. It is an oxidative stress inducer and a candidate marker for assessing cardiovascular risk factors in obesity. It can induce oxidative stress and inflammation and promote atherosclerosis.
Pack SizePriceAvailabilityQuantity
1 mg$48In Stock
5 mg$147In Stock
10 mg$239In Stock
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Purity:99.24%
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Product Introduction

Bioactivity
Description
7 Beta-Hydroxycholesterol (7β-Hydroxycholesterol) is an oxysterol contained in animal-derived foods. It is an oxidative stress inducer and a candidate marker for assessing cardiovascular risk factors in obesity. It can induce oxidative stress and inflammation and promote atherosclerosis.
In vitro
b>METHODS: Human NCI-H460 lung cancer cells were treated with 7β-Hydroxycholesterol (10, 20 and 30 μM for 14 days) and subjected to a clonogenic survival assay.
RESULTS: 7β-Hydroxycholesterol inhibited the clonogenic survival of NCI-H460 cells in a dose-dependent manner, with survival rates of 102%, 75%, 35% and 12% at concentrations of 5, 10, 20 and 30 μM, respectively. [1]
Alias7β-Hydroxycholesterol
Chemical Properties
Molecular Weight402.65
FormulaC27H46O2
Cas No.566-27-8
SmilesC[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=C[C@@H]3O)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCCC(C)C)C)[H])[H]
Relative Density.1.03 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 80 mg/mL (198.68 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.4835 mL12.4177 mL24.8355 mL124.1773 mL
5 mM0.4967 mL2.4835 mL4.9671 mL24.8355 mL
10 mM0.2484 mL1.2418 mL2.4835 mL12.4177 mL
20 mM0.1242 mL0.6209 mL1.2418 mL6.2089 mL
50 mM0.0497 mL0.2484 mL0.4967 mL2.4835 mL
100 mM0.0248 mL0.1242 mL0.2484 mL1.2418 mL

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Keywords

MAPKLDLCalcium Channel7b-Hydroxycholesterol7Beta-Hydroxycholesterol7BetaHydroxycholesterol7Beta Hydroxycholesterol
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