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9(S)-HpOTrE, a monohydroperoxy polyunsaturated fatty acid, is produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in 9,16-dihydroperoxy acid formation. The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via the formation of an unstable epoxide.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μg | $275 | 35 days | |
500 μg | $1,080 | 35 days | |
1 mg | $1,890 | 35 days |
Description | 9(S)-HpOTrE, a monohydroperoxy polyunsaturated fatty acid, is produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in 9,16-dihydroperoxy acid formation. The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via the formation of an unstable epoxide. |
Molecular Weight | 310.434 |
Formula | C18H30O4 |
Cas No. | 111004-08-1 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Solubility Information | DMSO: >50 mg/mL (from 13(S)-HODE) PBS (pH 7.2): >1 mg/mL (from 13(S)-HODE) DMF: >50 mg/mL (from 13(S)-HODE) Ethanol: >50 mg/mL (from 13(S)-HODE) |
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