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9-Propenyladenine

9-Propenyladenine (9-PA) is a mutagenic impurity in tenofovir disoproxil fumarate (TDF).

Catalog No. T12127Cas No. 1446486-33-4

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9-Propenyladenine

Catalog No. T12127Cas No. 1446486-33-4

9-Propenyladenine (9-PA) is a mutagenic impurity in tenofovir disoproxil fumarate (TDF).

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
5 mg	$327	7-10 days
10 mg	$541	7-10 days
1 mL x 10 mM (in DMSO)	$198	7-10 days

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Product Introduction

Bioactivity

Description	9-Propenyladenine (9-PA) is a mutagenic impurity in tenofovir disoproxil fumarate (TDF).
Alias	Mutagenic Impurity of Tenofovir Disoproxil, Tenofovir Impurity 2

Chemical Properties

Molecular Weight	175.19
Formula	C₈H₉N₅
Cas No.	1446486-33-4

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 29 mg/mL (165.53 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	5.7081 mL	28.5404 mL	57.0809 mL	285.4044 mL
5 mM	1.1416 mL	5.7081 mL	11.4162 mL	57.0809 mL
10 mM	0.5708 mL	2.8540 mL	5.7081 mL	28.5404 mL
20 mM	0.2854 mL	1.4270 mL	2.8540 mL	14.2702 mL
50 mM	0.1142 mL	0.5708 mL	1.1416 mL	5.7081 mL
100 mM	0.0571 mL	0.2854 mL	0.5708 mL	2.8540 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

9 Propenyladenine9-Propenyladenine9Propenyladenine