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AMY-101

Catalog No. TP2139Cas No. 1427001-89-5
Alias Cp40

AMY-101 is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM). AMY-101 shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.

AMY-101
Other Forms of AMY-101:
AMY-101 TFATP2139L1789738-04-0
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AMY-101 acetateT64692
View details

AMY-101

Catalog No. TP2139Alias Cp40Cas No. 1427001-89-5
AMY-101 is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM). AMY-101 shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.
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Product Introduction

Bioactivity
Description
AMY-101 is a peptidic inhibitor of the central complement component C3 (KD: 0.5 nM). AMY-101 shows a favorable anti-inflammatory activity in models with COVID-19 severe pneumonia with systemic hyper inflammation.
Targets&IC50
C3:(kd)0.5 nM
AliasCp40
Chemical Properties
Molecular Weight1789.11
FormulaC83H117N23O18S2
Cas No.1427001-89-5
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

AMY 101AMY-101AMY101
Related Tags: buy AMY-101 | purchase AMY-101 | AMY-101 cost | order AMY-101 | AMY-101 chemical structure | AMY-101 formula | AMY-101 molecular weight
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