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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Acid-PEG5-TEMPO is a PEG-based linker for PROTACs, joining two essential ligands crucial for PROTAC molecule formation, and facilitates selective protein degradation using the ubiquitin-proteasome system within cells. |
In vitro | PROTACs utilize two distinct ligands, connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets the protein of interest. They harness the intracellular ubiquitin-proteasome system to selectively degrade specific proteins[1]. |
Molecular Weight | 491.602 |
Formula | C23H43N2O9 |
Cas No. | 2055040-79-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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