Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship and it is used in treatment of osteoarthritis pain[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,670.00 | |
50 mg | 6-8 weeks | $ 2,180.00 | |
100 mg | 6-8 weeks | $ 2,800.00 |
Description | Autotaxin-IN-1 is a potent autotaxin inhibitor, which has favorable potency (IC50=2.2 nM), PK properties, and a robust PK/PD relationship and it is used in treatment of osteoarthritis pain[1]. |
Targets&IC50 | ATX:2 nM |
In vivo | Autotaxin-IN-1 (p.o.; 10 mg/kg) has Cmax of 660 nM and AUC of 3440 nM?h[1]. Autotaxin-IN-1 (i.v.; 1.0mg/kg) has T1/2 of 1.14 hours[1]. |
Molecular Weight | 405.45 |
Formula | C21H23N7O2 |
CAS No. | 1619971-30-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Autotaxin-IN-1 1619971-30-0 Metabolism PDE AutotaxinIN1 Autotaxin IN 1 inhibitor inhibit