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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Azido-PEG8-hydrazide, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands linked by a connector: one targets an E3 ubiquitin ligase, and the other targets the desired protein. These compounds utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 481.54 |
Formula | C19H39N5O9 |
Cas No. | 2353410-11-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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