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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis-PEG7-acid and bis-PEG6-propionic acid are chemical compounds that serve as linkers in the synthesis of PROTACs and antibody-drug conjugates (ADCs), respectively. Bis-PEG7-acid is a PEG-based PROTAC linker, while bis-PEG6-propionic acid is a cleavable ADC linker[1]. |
In vitro | PROTACs consist of two ligands joined by a linker: one targets an E3 ubiquitin ligase and the other targets the desired protein, thereby leveraging the ubiquitin-proteasome system for selective protein degradation. ADCs (antibody-drug conjugates) comprise an antibody linked to a cytotoxin via an ADC linker. |
Molecular Weight | 426.46 |
Formula | C18H34O11 |
Cas No. | 94376-75-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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