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D-JBD19 [D-JNKI1-TAT (residues 153-163)] is a non-permeable peptide that offers neuroprotective effects.
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Description | D-JBD19 [D-JNKI1-TAT (residues 153-163)] is a non-permeable peptide that offers neuroprotective effects. |
In vitro | D-JBD19 is a non-permeable peptide, analogous to the dJNKi peptide [1]. |
In vivo | Compared to D-JNKI1, D-JBD19 demonstrates neuroprotective effects following middle cerebral artery occlusion. A dose of 15.7 ng of either D-JBD19 or D-JNKI1, or alternatively, 1570 ng of D-JBD19, was administered intracerebroventricularly immediately after ischemia onset. The animals were euthanized 24 hours post-injection. Notably, D-JBD19 requires a 100-fold higher dosage to achieve similar protective efficacy as D-JNKI1 [2]. |
Molecular Weight | 2250.597 |
Formula | C99H164N32O28 |
Cas No. | 954134-42-0 |
Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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