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DU717

Catalog No. T11109Cas No. 59943-31-6
Alias DU-717

DU717 is an antihypertensive agent.

DU717

DU717

Purity: 99.64%
Catalog No. T11109Alias DU-717Cas No. 59943-31-6
DU717 is an antihypertensive agent.
Pack SizePriceAvailabilityQuantity
1 mg$197In Stock
5 mg$392In Stock
10 mg$672In Stock
25 mg$981In Stock
50 mg$1,350In Stock
100 mg$1,780In Stock
1 mL x 10 mM (in DMSO)$427In Stock
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Purity:99.64%
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Product Introduction

Bioactivity
Description
DU717 is an antihypertensive agent.
In vivo
A gas chromatographic method for the determination of DU717, a novel antihypertensive drug in plasma, was established.The plasma concentration of DU717 ranged from 10-150 ng /mL with a RSD of 6.2%.The minimum detection concentration is 1 ng/mL.Plasma levels of DU717 in spontaneously hypertensive and normal-blood pressure rats were also measured.
AliasDU-717
Chemical Properties
Molecular Weight314.79
FormulaC12H15ClN4O2S
Cas No.59943-31-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (158.84 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1767 mL15.8836 mL31.7672 mL158.8360 mL
5 mM0.6353 mL3.1767 mL6.3534 mL31.7672 mL
10 mM0.3177 mL1.5884 mL3.1767 mL15.8836 mL
20 mM0.1588 mL0.7942 mL1.5884 mL7.9418 mL
50 mM0.0635 mL0.3177 mL0.6353 mL3.1767 mL
100 mM0.0318 mL0.1588 mL0.3177 mL1.5884 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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