Powder: -20°C for 3 years | In solvent: -80°C for 1 year
EGFR mutant- in-1, A 5-methylpyrimidopyridone derivative are effective selective EGFRL858R/T790M/C797S mutant inhibitors with IC50 of 27.5 nM, which significantly weakened EGFRWT effect.
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Description | EGFR mutant- in-1, A 5-methylpyrimidopyridone derivative are effective selective EGFRL858R/T790M/C797S mutant inhibitors with IC50 of 27.5 nM, which significantly weakened EGFRWT effect. |
Targets&IC50 | EGFR (WT):>1.0 μM , EGFR (L858R/T790M/C797S):27.5 nM |
Molecular Weight | 632.17 |
Formula | C34H39ClFN7O2 |
CAS No. | T11164 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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EGFR mutant-IN-1 T11164 Angiogenesis JAK/STAT signaling Tyrosine Kinase/Adaptors EGFR EGFR mutant IN 1 EGFR mutantIN1 inhibitor inhibit