Powder: -20°C for 3 years | In solvent: -80°C for 1 year
MCU-i11 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 437.00 | |
10 mg | In stock | $ 646.00 | |
25 mg | In stock | $ 987.00 | |
50 mg | In stock | $ 1,380.00 | |
100 mg | In stock | $ 1,860.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 556.00 |
Description | MCU-i11 is a novel negative modulator of the MCU, binding MICU1 and impairing muscle cell growth. |
In vitro | Mitochondrial Ca2+ uptake in mouse embryonic fibroblasts (MEFs), MDA-MB-231, and HEK293T cell lines were measured upon treatment with 10 μM compound. MCU-i11 reduced mitochondrial Ca2+ uptake in all tested cell lines, indicating the existence of a conserved mechanism. MCU-i11 had no effect on cell viability. [1] |
Molecular Weight | 532.61 |
Formula | C28H28N4O5S |
CAS No. | 902903-59-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (84.49 mM)
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
MCU-i11 902903-59-7 Others MCUi11 MCU i11 inhibitor inhibit