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ML267

ML267 (4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate) is a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth[1].

Catalog No. T64340Cas No. 1542213-67-1

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Purity:99.80%

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COA HNMR HPLC

ML267

Catalog No. T64340Cas No. 1542213-67-1

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Pack Size	Price	Availability
1 mg	$89	In Stock
5 mg	$202	In Stock
10 mg	$296	In Stock
25 mg	$473	In Stock
50 mg	$672	In Stock
100 mg	$893	In Stock
200 mg	$1,180	In Stock
1 mL x 10 mM (in DMSO)	$259	In Stock

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Product Introduction

Bioactivity

Description	ML267 (4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate) is a potent inhibitor of bacterial phosphopantetheinyl transferase that attenuates secondary metabolism and thwarts bacterial growth[1].
Alias	4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-methoxypyridin-2-yl)piperazine-1-carbothioamide trifluoroacetate

Chemical Properties

Molecular Weight	545.89
Formula	C₁₉H₁₈ClF₆N₅O₃S
Cas No.	1542213-67-1

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 60 mg/mL (109.91 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.8319 mL	9.1594 mL	18.3187 mL	91.5935 mL
5 mM	0.3664 mL	1.8319 mL	3.6637 mL	18.3187 mL
10 mM	0.1832 mL	0.9159 mL	1.8319 mL	9.1594 mL
20 mM	0.0916 mL	0.4580 mL	0.9159 mL	4.5797 mL
50 mM	0.0366 mL	0.1832 mL	0.3664 mL	1.8319 mL
100 mM	0.0183 mL	0.0916 mL	0.1832 mL	0.9159 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

ML-267ML 267ML267