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Macropa-NH2 hydrochloride

Catalog No. T11938Cas No. 2443966-86-5

Macropa-NH2 hydrochloride is a ligand with nickel coordination activity that forms stable complexes with metals.

Macropa-NH2 hydrochloride

Macropa-NH2 hydrochloride

Purity: 98.49%
Catalog No. T11938Cas No. 2443966-86-5
Macropa-NH2 hydrochloride is a ligand with nickel coordination activity that forms stable complexes with metals.
Pack SizePriceAvailabilityQuantity
1 mg$165In Stock
5 mg$413In Stock
10 mg$689In Stock
25 mg$1,450In Stock
50 mg$2,360In Stock
100 mg$3,730In Stock
1 mL x 10 mM (in DMSO)$549In Stock
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Purity:98.49%
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Product Introduction

Bioactivity
Description
Macropa-NH2 hydrochloride is a ligand with nickel coordination activity that forms stable complexes with metals.
In vitro
Macropa-NH2 hydrochloride, as a precursor of Macropa-NCS, is a promising therapeutic radiopharmaceutical that can be used for the treatment of soft tissue metastases[1].
Chemical Properties
Molecular Weight584.06
FormulaC26H38ClN5O8
Cas No.2443966-86-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 80 mg/mL (136.97 mM), Sonication is recommended.
DMSO: 83.33 mg/mL (142.67 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM1.7122 mL8.5608 mL17.1215 mL85.6076 mL
5 mM0.3424 mL1.7122 mL3.4243 mL17.1215 mL
10 mM0.1712 mL0.8561 mL1.7122 mL8.5608 mL
20 mM0.0856 mL0.4280 mL0.8561 mL4.2804 mL
50 mM0.0342 mL0.1712 mL0.3424 mL1.7122 mL
100 mM0.0171 mL0.0856 mL0.1712 mL0.8561 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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