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Methylamino-PEG1-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands crucial for PROTAC molecule formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Methylamino-PEG1-acid is a PEG-based linker for PROTACs, facilitating the connection of two essential ligands crucial for PROTAC molecule formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two ligands connected by a linker: one binds to an E3 ubiquitin ligase and the other to the target protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 147.17 |
Formula | C6H13NO3 |
Cas No. | 1367918-21-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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