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NH2-C6-NH-Boc

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Catalog No. T18487Cas No. 51857-17-1

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

NH2-C6-NH-Boc

NH2-C6-NH-Boc

🥰Excellent
Purity: 99.97%
Catalog No. T18487Cas No. 51857-17-1
NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].
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Purity:99.97%
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Product Introduction

Bioactivity
Description
NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].
Chemical Properties
Molecular Weight216.32
FormulaC11H24N2O2
Cas No.51857-17-1
SmilesC(NCCCCCCN)(OC(C)(C)C)=O
Relative Density.0.965 g/cm3 at 20℃ (lit.)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
Ethanol: 100 mg/mL (462.28 mM), Sonication is recommended.
Solution Preparation Table
Ethanol
1mg5mg10mg50mg
1 mM4.6228 mL23.1139 mL46.2278 mL231.1391 mL
5 mM0.9246 mL4.6228 mL9.2456 mL46.2278 mL
10 mM0.4623 mL2.3114 mL4.6228 mL23.1139 mL
20 mM0.2311 mL1.1557 mL2.3114 mL11.5570 mL
50 mM0.0925 mL0.4623 mL0.9246 mL4.6228 mL
100 mM0.0462 mL0.2311 mL0.4623 mL2.3114 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
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2 Enter the in vivo formulation:
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Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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