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Ac4ManNAz
Catalog No. T14093Cas No. 361154-30-5
Ac4ManNAz is an azide-containing metabolic glycoprotein labeling reagent that can selectively modify proteins and can be used for cell labeling, tracking, and proteomic analysis.
Ac4ManNAz
Catalog No. T14093Cas No. 361154-30-5
Ac4ManNAz is an azide-containing metabolic glycoprotein labeling reagent that can selectively modify proteins and can be used for cell labeling, tracking, and proteomic analysis.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $32 | In Stock | |
| 5 mg | $50 | In Stock | |
| 10 mg | $80 | In Stock | |
| 25 mg | $178 | In Stock | |
| 50 mg | $268 | In Stock | |
| 100 mg | $397 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $64 | In Stock |
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Purity:98.42%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | Ac4ManNAz is an azide-containing metabolic glycoprotein labeling reagent that can selectively modify proteins and can be used for cell labeling, tracking, and proteomic analysis. |
| In vitro | METHODS: A549 cells were cultured with 0, 10, and 50 μM Ac4ManNAz, and total RNA was extracted to evaluate the quantity and quality of total RNA. RESULTS Compared with untreated A549 cells, mRNA expression levels changed 7-fold; biological functional pathways related to urogenital cancer and cell invasion were significantly activated, while signal transduction related to cell maturation and surface receptor ligation was inhibited. [1] METHODS: Ac4MAnNAz (0-50 μM) treated A549 cells, and analyzed the channel activation, proliferation ability and vitality of A549 cells treated with Ac4ManNAz; Ac4ManNAz (0, 10, 20, 50 μM, 30 hours) treated A549 cells, and performed wounds on A549 cells Healing and invasion assays. RESULTS There was no significant change in the activities of TRP M7 and VSOR Cl channels, and the growth rate of A549 cells was reduced by 10%; as the concentration of Ac4ManNAz increased, the migration and invasion abilities gradually decreased, [1] |
| Molecular Weight | 430.37 |
| Formula | C16H22N4O10 |
| Cas No. | 361154-30-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (116.18 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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