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Orellanine

Name: Orellanine
Brand: TargetMol
SKU: T33817
Price: 397 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T33817Cas No. 37338-80-0

Alias 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one

Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat liver mitochondria.

Orellanine

🥰Excellent

Catalog No. T33817Alias 2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-oneCas No. 37338-80-0

Pack Size	Price	Availability
1 mg	$397	In Stock
5 mg	$969	In Stock
10 mg	$1,310	In Stock
25 mg	$1,930	In Stock
50 mg	$2,620	In Stock
100 mg	$3,530	In Stock
1 mL x 10 mM (in DMSO)	$749	In Stock

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Orellanine is a nephrotoxic compound extracted from the mushroom Cortinarius orellanus. Orellanine strongly inhibits the synthesis of macromolecules (Proteins, RNA and DNA) in Madin-Darby canine kidney cells and in rat liver mitochondria.
Alias	2-(1,3-dihydroxy-4-oxopyridin-2-yl)-1,3-dihydroxypyridin-4-one

Chemical Properties

Molecular Weight	252.18
Formula	C₁₀H₈N₂O₆
Cas No.	37338-80-0
Smiles	OC1=C(N(=O)=CC=C1O)C2=C(O)C(O)=CC=N2=O
Relative Density.	1.77 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 10 mg/mL (39.65 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9654 mL	19.8271 mL	39.6542 mL	198.2711 mL
5 mM	0.7931 mL	3.9654 mL	7.9308 mL	39.6542 mL
10 mM	0.3965 mL	1.9827 mL	3.9654 mL	19.8271 mL
20 mM	0.1983 mL	0.9914 mL	1.9827 mL	9.9136 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Orellanine