Powder: -20°C for 3 years | In solvent: -80°C for 1 year
PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, and 2.2 nM for TrkA, TrkB, and TrkC) with anti-hyperalgesic effect.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 8-10 weeks | $ 1,820.00 | |
50 mg | 8-10 weeks | $ 2,380.00 | |
100 mg | 8-10 weeks | $ 3,100.00 |
Description | PF-06733804 is a potent inhibitor of pan-Trk in cell-based assays (IC50s: 8.4 nM, 6.2 nM, and 2.2 nM for TrkA, TrkB, and TrkC) with anti-hyperalgesic effect. |
Targets&IC50 | TrkA:8.4 nM , TrkB:6.2 nM (in cell-based assays), TrkC:2.2 nM (in cell-based assays) |
In vitro | In the FP and PX assay, PF-06733804 inhibits hERG with IC50s of 79 μM and 88 μM, respectively. |
Molecular Weight | 474.38 |
Formula | C20H19F5N4O4 |
CAS No. | 1873373-33-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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PF-06733804 1873373-33-1 Tyrosine Kinase/Adaptors Trk receptor PF 06733804 PF06733804 inhibitor inhibit