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RTC-30

Catalog No. T18652Cas No. 1423077-95-5

RTC-30, an optimized phenothiazine compound, possesses potent anti-cancer properties and is formulated with a hydroxylated linker (N) to enhance its oral bioavailability[1].

RTC-30

RTC-30

Catalog No. T18652Cas No. 1423077-95-5
RTC-30, an optimized phenothiazine compound, possesses potent anti-cancer properties and is formulated with a hydroxylated linker (N) to enhance its oral bioavailability[1].
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Product Introduction

Bioactivity
Description
RTC-30, an optimized phenothiazine compound, possesses potent anti-cancer properties and is formulated with a hydroxylated linker (N) to enhance its oral bioavailability[1].
In vitro
RTC-30 (0-40 μM; 48 hours) inhibits H1650 lung adenocarcinoma cell growth with a GI50 of 15 μM[1].
Chemical Properties
Molecular Weight492.51
FormulaC24H23F3N2O4S
Cas No.1423077-95-5
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 15 mg/mL (30.46 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.0304 mL10.1521 mL20.3042 mL101.5208 mL
5 mM0.4061 mL2.0304 mL4.0608 mL20.3042 mL
10 mM0.2030 mL1.0152 mL2.0304 mL10.1521 mL
20 mM0.1015 mL0.5076 mL1.0152 mL5.0760 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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