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Senazodan is a sensitiser of Ca2+, and shows inhibition effect on PDE III.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | Senazodan is a sensitiser of Ca2+, and shows inhibition effect on PDE III. |
In vitro | Senazodan directly affects actin-myosin crossbridge kinetics, increases myosin ATPase activity[1], enhances Ca2+ binding to myofilaments and purified cardiac troponin C, and improves contractility in guinea-pig papillary muscles by inhibiting PDE III, resulting in a concentration-dependent increase in tension development[2]. |
Molecular Weight | 266.3 |
Formula | C15H14N4O |
Cas No. | 98326-32-0 |
Relative Density. | 1.3g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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