Powder: -20°C for 3 years | In solvent: -80°C for 1 year
TD-106 is a modulator of cereblon (CRBN), and can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mL * 10 mM (in DMSO) | 5 days | $ 318.00 |
Description | TD-106 is a modulator of cereblon (CRBN), and can be used for targeted protein degradation. BRD4 PROTACs with TD-106 induce BRD4 degradation. |
In vitro | TD-106 inhibits the proliferation of NCI-H929 myeloma cell line with an CC50?of?0.039?μM, and induces the degradation of IKZF1/3 in NCI-H929?cells. |
In vivo | In SCID mice with TMD-8 xenograft model, TD-106 possesses anti-myeloma activity . |
Molecular Weight | 273.25 |
Formula | C12H11N5O3 |
CAS No. | 2250288-69-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 125 mg/mL (457.46 mM)
You can also refer to dose conversion for different animals. More
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TD-106 2250288-69-6 Others TD106 TD 106 inhibitor inhibit