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XEN907

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Catalog No. T17263Cas No. 912656-34-9

XEN907 is a novel spiro oxindole NaV1.7 blocker. XEN907 also inhibits hNaV1.7 (IC50: 3 nM).

XEN907

XEN907

🥰Excellent
Purity: 99.26%
Catalog No. T17263Cas No. 912656-34-9
XEN907 is a novel spiro oxindole NaV1.7 blocker. XEN907 also inhibits hNaV1.7 (IC50: 3 nM).
Pack SizePriceAvailabilityQuantity
2 mg$38In Stock
5 mg$58In Stock
10 mg$86In Stock
25 mg$143In Stock
50 mg$215In Stock
1 mL x 10 mM (in DMSO)$59In Stock
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Purity:99.26%
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Product Introduction

Bioactivity
Description
XEN907 is a novel spiro oxindole NaV1.7 blocker. XEN907 also inhibits hNaV1.7 (IC50: 3 nM).
Targets&IC50
Nav1.7:3 nM (IC50)
Chemical Properties
Molecular Weight351.4
FormulaC21H21NO4
Cas No.912656-34-9
SmilesCCCCCN1C(=O)C2(COc3cc4OCOc4cc23)c2ccccc12
Relative Density.1.34 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 60 mg/ml (170.75 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.8458 mL14.2288 mL28.4576 mL142.2880 mL
5 mM0.5692 mL2.8458 mL5.6915 mL28.4576 mL
10 mM0.2846 mL1.4229 mL2.8458 mL14.2288 mL
20 mM0.1423 mL0.7114 mL1.4229 mL7.1144 mL
50 mM0.0569 mL0.2846 mL0.5692 mL2.8458 mL
100 mM0.0285 mL0.1423 mL0.2846 mL1.4229 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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