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Acetyl-CoA Carboxylase-IN-1
🥰Excellent
Catalog No. T72180Cas No. 179343-23-8
Alias ACC-IN-1
Acetyl-CoA Carboxylase-IN-1 (ACC-IN-1) is an efficient inhibitor of acetyl-CoA carboxylase (ACC), with antibacterial activity, and can be applied in the study of metabolic diseases.
Acetyl-CoA Carboxylase-IN-1
🥰Excellent
Catalog No. T72180Alias ACC-IN-1Cas No. 179343-23-8
Acetyl-CoA Carboxylase-IN-1 (ACC-IN-1) is an efficient inhibitor of acetyl-CoA carboxylase (ACC), with antibacterial activity, and can be applied in the study of metabolic diseases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $30 | In Stock | |
| 5 mg | $58 | In Stock | |
| 10 mg | $98 | In Stock | |
| 25 mg | $198 | In Stock | |
| 50 mg | $373 | In Stock | |
| 100 mg | $623 | In Stock | |
| 200 mg | $887 | In Stock |
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NDI-010976, ND-630, GS-0976
T71841434635-54-7
Firsocostat (GS-0976) is an inhibitor of acetyl-CoA carboxylase (ACC) dimerization that inhibits human ACC1 and ACC2 activity (IC50s of 2.1 and 6.1 nM, respectively)
- $88
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CitedContact us for more batch information
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Product Introduction
Bioactivity
Chemical Properties
| Description | Acetyl-CoA Carboxylase-IN-1 (ACC-IN-1) is an efficient inhibitor of acetyl-CoA carboxylase (ACC), with antibacterial activity, and can be applied in the study of metabolic diseases. |
| In vitro | Acetyl-CoA Carboxylase-IN-1 (0.012-25 μM) exhibits antibacterial activity in Escherichia coli with MIC values of >25, 3.13, 25, 0.39, 1.56, and 0.1 μM for WT, WT+ PMBN, ΔacrAB, ΔacrAB+PMBN, ΔtolC, and ΔtolC+ PMBN, respectively.[1] |
| Alias | ACC-IN-1 |
| Molecular Weight | 395.05 |
| Formula | C13H9Br2N5 |
| Cas No. | 179343-23-8 |
| Smiles | BrC=1C=CC=C(Br)C1C=2C=C3C=NC(=NC3=NC2N)N |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 30 mg/mL (75.94 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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