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ACG416B

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Catalog No. T40903Cas No. 795316-15-3

ACG416B (compound 18) exhibits formidable inhibitory effects on choline kinase (ChoK), with an IC 50 measurement of 0.4 μM. Notably, ACG416B demonstrates superior inhibitory activities against HT-29 human colon cancer cells, resulting in pronounced antiproliferative effects.

ACG416B

ACG416B

😃Good
Catalog No. T40903Cas No. 795316-15-3
ACG416B (compound 18) exhibits formidable inhibitory effects on choline kinase (ChoK), with an IC 50 measurement of 0.4 μM. Notably, ACG416B demonstrates superior inhibitory activities against HT-29 human colon cancer cells, resulting in pronounced antiproliferative effects.
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Product Introduction

Bioactivity
Description
ACG416B (compound 18) exhibits formidable inhibitory effects on choline kinase (ChoK), with an IC 50 measurement of 0.4 μM. Notably, ACG416B demonstrates superior inhibitory activities against HT-29 human colon cancer cells, resulting in pronounced antiproliferative effects.
Chemical Properties
Molecular Weight708.542
FormulaC38H36Br2N4
Cas No.795316-15-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

ACG416BACG-416B
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