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ACG548B

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Catalog No. T40904Cas No. 795316-16-4

ACG548B (compound 24) is a highly effective inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50 values of 1.78 μM and 0.496 μM, respectively, exhibiting greater affinity for AChE and demonstrating selectivity over BChE and ChoK (choline kinase).

ACG548B

ACG548B

😃Good
Catalog No. T40904Cas No. 795316-16-4
ACG548B (compound 24) is a highly effective inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50 values of 1.78 μM and 0.496 μM, respectively, exhibiting greater affinity for AChE and demonstrating selectivity over BChE and ChoK (choline kinase).
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Product Introduction

Bioactivity
Description
ACG548B (compound 24) is a highly effective inhibitor of acetyl- and butyrylcholinesterase (AChE and BChE) with IC50 values of 1.78 μM and 0.496 μM, respectively, exhibiting greater affinity for AChE and demonstrating selectivity over BChE and ChoK (choline kinase).
Chemical Properties
Molecular Weight777.43
FormulaC38H34Br2Cl2N4
Cas No.795316-16-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

ACG-548BACG548B
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