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Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | Backorder |
Description | Alclometasone (7a-Chloro-16a-methyl prednisolone), a glucocorticoid, inhibits leukocytes from releasing pro-inflammatory mediators. It is effective in treating corticosteroid-responsive dermatoses such as atopic dermatitis, psoriasis, allergic dermatitis, and eczema [1]. |
In vivo | The prodrug of alclometasone is alclometasone dipropionate[2]. Alclometasone dipropionate (subcutaneous injection; 1 % (w/v) arabic gum; 2 weeks) inhibits the activity of androgen-dependent cytochrome P450 and O-depropylation activity as a dose-dependent manner in male Slc-Wistar strain rats. Alclometasone dipropionate (subcutaneous injection; 1 % (w/v) arabic gum; 2 weeks) has no effects on hepatic drug metabolism in female rats or DS strain mice[2]. |
Alias | 7a-Chloro-16a-methyl prednisolone |
Molecular Weight | 408.92 |
Formula | C22H29ClO5 |
Cas No. | 67452-97-5 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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