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Ald-CH2-PEG3-CH2-Boc

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Catalog No. T14158Cas No. 2100306-54-3

Ald-CH2-PEG3-CH2-Boc, a PEG- and Alkyl/ether-based PROTAC linker, is utilized for the synthesis of SGK3 kinase PROTAC degrader[1].

Ald-CH2-PEG3-CH2-Boc

Ald-CH2-PEG3-CH2-Boc

😃Good
Catalog No. T14158Cas No. 2100306-54-3
Ald-CH2-PEG3-CH2-Boc, a PEG- and Alkyl/ether-based PROTAC linker, is utilized for the synthesis of SGK3 kinase PROTAC degrader[1].
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Product Introduction

Bioactivity
Description
Ald-CH2-PEG3-CH2-Boc, a PEG- and Alkyl/ether-based PROTAC linker, is utilized for the synthesis of SGK3 kinase PROTAC degrader[1].
In vitro
PROTACs, comprising two ligands joined by a linker—one binding an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system [UPS] to selectively degrade target proteins.
Chemical Properties
Molecular Weight306.35
FormulaC14H26O7
Cas No.2100306-54-3
Relative Density.1.071 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

PEGsAlkyl/etherAld-CH2-PEG3-CH2-BocAld-CH-2-PEG3-CH2-BocAldCH2PEG3CH2BocAld CH2 PEG3 CH2 Boc
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