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Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $45 | 5 days | |
10 mg | $63 | 5 days |
Description | Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one ligand targets an E3 ubiquitin ligase, and the other binds to the target protein. Utilizing the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins [1]. |
Molecular Weight | 380.44 |
Formula | C19H28N2O6 |
Cas No. | 1807503-90-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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