ald ph peg2 nh boc

Ald-Ph-PEG2-NH-Boc is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH-bis(C1-Boc) is an uncleavable linker used for antibody-drug conjugates (ADC).

NH2-C2-NH-Boc (PROTAC Linker 22), an alkyl chain-based PROTAC linker, can be used in the synthesis of PROTACs.

NH2-C4-NH-Boc (compound 15) is a PROTAC linker of the Alkyl ether class, suitable for synthesizing various PROTAC molecules.

NH2-C5-NH-Boc (PROTAC Linker 23) is an alkyl chain-based PROTAC linker used in the synthesis of PROTACs.

Boc-NH-PEG1-OH is a PEG-based PROTAC linker utilized in the synthesis of PROTACs.

Boc-NH-PEG4-CH2COOH is a cleavable ADC linker utilized in the development of antibody-drug conjugates (ADC)[1].

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

Boc-NH-PEG7-Tos (t-Boc-N-Amido-PEG7-Tos) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG11-OH, a PEG-based PROTAC linker, is utilized in PROTAC synthesis.

Mal-PEG2-C2-Boc (Mal-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. Mal-PEG2-C2-Boc can be used in the synthesis of PROTACs.

Ald-Ph-NHS ester is a non-cleavable linker utilized in antibody-drug conjugation (ADC).

Boc-NH-PEG3 (PROTAC Linker 10) is a PEG derivative featuring a hydroxyl group and a Boc-protected amino group, used as a PROTAC linker.

Boc-NH-C12-NH2 is an alkyl ether-based PROTAC linker suitable for use in PROTAC synthesis.

Boc-NH-O-C1-NHS ester, an alkyl ether-based PROTAC linker, is utilized in PROTAC synthesis.

Boc-NH-PEG8-CH2CH2NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.

Cbz-NH-PEG2-CH2COOH is a PEG-based PROTAC linker [PROTACs] useful in PROTAC synthesis.

Boc-NH-PEG12-NH2 (NHBoc-PEG12-amine) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Boc-NH-PEG3-NHS ester is a PEG-based linker utilized in the synthesis of PROTACs.

Boc-NH-PEG4-CH2CH2NH2 is a cleavable 5-unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1].

S-acetyl-PEG2-Boc (S-Acetyl-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. S-acetyl-PEG2-Boc can be used in the synthesis of PROTACs.

Bromo-PEG2-CH2-Boc is a PEG-based PROTAC linker employed in PROTAC synthesis [1].

Boc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-PEG11-NH2 is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Boc-NH-C4-acid is a PROTAC linker of the Alkyl ether class, utilized in the synthesis of PROTAC1 for the degradation of EED, EZH2, and SUZ12 in [PRC2].

Boc-NH-C6-Br is a cleavable linker used in antibody-drug conjugates (ADC).

Boc-NH-PEG3-CH2COOH, a PEG-based PROTAC linker, can be utilized in PROTAC synthesis [1].

Boc-NH-PEG6-CH2COOH is a PEG-based PROTAC linker employed in PROTAC synthesis.

Hydroxy-PEG4-(CH2)2-Boc is an uncleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) and can also be employed in the synthesis of PROTAC.

Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) is a long-acting fibroblast growth factor 21 (FGF21) analog and FGF21-receptor agonist, suitable for development as a potential treatment for T2DM.

Boc-NH-PEG8-CH2CH2COOH is a PEG-based PROTAC linker utilized in PROTAC synthesis.

Thalidomide-NH-C4-NH-Boc is a synthesized conjugate used in PROTAC technology, combining a Thalidomide-based cereblon ligand with a linker.

Thalidomide-NH-(CH2)2-NH2 TFA, an alkyl-modified derivative of Thalidomide, functions as a Cereblon ligand to recruit CRBN proteins and serves as a crucial intermediate in the synthesis of CRBN-based PROTAC molecules targeting the SHP2 protein.

m-PEG2-O-Ph-3-NH2 is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules. This linker enables selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

Chloro-PEG2-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Tetrazine-Ph-NHCO-PEG6-NH-Boc is a PEG-based PROTAC linker used for PROTAC synthesis [1].

DBCO-C2-PEG4-NH-Boc is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

2-(Azido-PEG2-amido)-13-propandiol is a Polyethylene glycol (PEG)-based PROTAC linker used for synthesizing PROTACs[1].

N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-derived linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Ald-Ph-PEG2-Boc is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a small molecule HaloPROTAC incorporating the (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker, capable of inducing degradation of GFP-HaloTag7 in cell-based assays [1].

Boc-Aminooxy-PEG2-bromide is a bifunctional, cleavable polyethylene glycol (PEG) linker used specifically in the synthesis of antibody-drug conjugates (ADCs) [1].

N-Mal-N-bis(PEG2-NH-Boc) is a polyethylene glycol (PEG) derived linker designed for synthesizing proteolysis targeting chimeras (PROTACs)[1].

Boc-NH-PEG6-azide, a PEG-based linker for PROTACs, joins two essential ligands crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

NH-bis(C2-PEG2-NH-Boc) is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system in cells.

Ald-Ph-amido-PEG4-propargyl is a non-cleavable, 4-unit polyethylene glycol (PEG) antibody-drug conjugate (ADC) linker used in ADC synthesis[1].

Boc-NH-PEG5-propargyl is a PEG-based linker for PROTACs, facilitating the binding of two essential ligands necessary for PROTAC formation. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.