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alphaSYN-IN-NAB2

🥰Excellent
Catalog No. T23709Cas No. 1504588-00-4
Alias NAB2, alphaSYN-IN-NAB2, alphaSYNINNAB2, alphaSYN inhibitor-NAB2, alphaSYN inhibitor NAB2

alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity. NAB2 promotes endosomal transport dependent on E3 ubiquitin ligase Rsp5/Nedd4. NAB2 identifies a viable molecular node in alpha-SYN biology that corrects multiple aspects of its underlying pathology, including dysfunctional endosomes and endoplasmic reticulum to Golgi vesicles transport. NAB2 is involved in cellular processes such as cell differentiation, apoptosis and stress response, and can be used to study cancer, neurodevelopment and neuronal activity.

alphaSYN-IN-NAB2

alphaSYN-IN-NAB2

🥰Excellent
Purity: 99.56%
Catalog No. T23709Alias NAB2, alphaSYN-IN-NAB2, alphaSYNINNAB2, alphaSYN inhibitor-NAB2, alphaSYN inhibitor NAB2Cas No. 1504588-00-4
alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity. NAB2 promotes endosomal transport dependent on E3 ubiquitin ligase Rsp5/Nedd4. NAB2 identifies a viable molecular node in alpha-SYN biology that corrects multiple aspects of its underlying pathology, including dysfunctional endosomes and endoplasmic reticulum to Golgi vesicles transport. NAB2 is involved in cellular processes such as cell differentiation, apoptosis and stress response, and can be used to study cancer, neurodevelopment and neuronal activity.
Pack SizePriceAvailabilityQuantity
1 mg$46In Stock
5 mg$95In Stock
10 mg$157In Stock
25 mg$297In Stock
50 mg$488In Stock
100 mg$733In Stock
500 mg$1,490In Stock
1 mL x 10 mM (in DMSO)$81In Stock
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Purity:99.56%
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Product Introduction

Bioactivity
Description
alphaSYN-IN-NAB2, a neuron-protective agent, is a protein encoded by the NAB2 gene. NAB2 effectively and selectively protects a variety of cells from alpha-SYN toxicity. NAB2 promotes endosomal transport dependent on E3 ubiquitin ligase Rsp5/Nedd4. NAB2 identifies a viable molecular node in alpha-SYN biology that corrects multiple aspects of its underlying pathology, including dysfunctional endosomes and endoplasmic reticulum to Golgi vesicles transport. NAB2 is involved in cellular processes such as cell differentiation, apoptosis and stress response, and can be used to study cancer, neurodevelopment and neuronal activity.
AliasNAB2, alphaSYN-IN-NAB2, alphaSYNINNAB2, alphaSYN inhibitor-NAB2, alphaSYN inhibitor NAB2
Chemical Properties
Molecular Weight389.88
FormulaC23H20ClN3O
Cas No.1504588-00-4
SmilesCC1=C(N2C=3C(=CC(C(NCC4=C(Cl)C=CC=C4)=O)=CC3)N=C2)C=C(C)C=C1
Relative Density.1.24 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 50 mg/mL (128.24 mM), Sonication is recommended.
Ethanol: 35.1 mg/mL (90.0 mM)
Solution Preparation Table
Ethanol/DMSO
1mg5mg10mg50mg
1 mM2.5649 mL12.8245 mL25.6489 mL128.2446 mL
5 mM0.5130 mL2.5649 mL5.1298 mL25.6489 mL
10 mM0.2565 mL1.2824 mL2.5649 mL12.8245 mL
20 mM0.1282 mL0.6412 mL1.2824 mL6.4122 mL
50 mM0.0513 mL0.2565 mL0.5130 mL2.5649 mL
DMSO
1mg5mg10mg50mg
100 mM0.0256 mL0.1282 mL0.2565 mL1.2824 mL

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Keywords

α-synucleinNAB-2NAB 2
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