Shopping Cart
- Remove All
Your shopping cart is currently empty
Amatuximab
🥰Excellent
Catalog No. T76671Cas No. 931402-35-6
Alias MORab-009
Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors.
Amatuximab
Amatuximab
🥰Excellent
Purity: 98.4% (SEC-HPLC)
Catalog No. T76671Alias MORab-009Cas No. 931402-35-6
Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $198 | In Stock | |
| 5 mg | $538 | In Stock | |
| 10 mg | $863 | In Stock | |
| 25 mg | $1,290 | In Stock | |
| 50 mg | $1,760 | In Stock | |
| 100 mg | $2,380 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreSelect Batch
Concentration:2.2 mg/mL
Purity:98.4% (SEC-HPLC)
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Amatuximab (MORab-009) is a humanized chimeric IgG1/k monoclonal antibody targeting cell surface mesothelin (MSLN) with antitumor activity for the treatment of solid tumors. |
| In vitro | Amatuximab (MORAb-009) is a murine-human chimeric monoclonal antibody with selective affinity for mesothelin (MSLN). In vitro, Amatuximab can induce antibody-dependent cell-mediated cytotoxicity (ADCC) against tumor cell lines expressing mesothelin and inhibit heterotypic cell adhesion between mesothelin-positive tumor cells and tumor cells expressing CA125[1]. |
| In vivo | In tumor xenograft studies, the combination treatment of Amatuximab and chemotherapy significantly reduces the growth of mesothelin-expressing tumors to a greater extent compared to the use of Amatuximab or chemotherapy alone[1]. |
| Alias | MORab-009 |
| Molecular Weight | 144.31 kDa |
| Cas No. | 931402-35-6 |
Storage & Solubility Information
| Storage | store at low temperature | store at -20°C | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
Preview
Related Tags: buy Amatuximab | purchase Amatuximab | Amatuximab cost | order Amatuximab | Amatuximab in vivo | Amatuximab in vitro | Amatuximab molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.