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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Aminooxy-PEG8-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands critical for PROTAC molecule formation, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, while the other targets the desired protein. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 493.98 |
Formula | C19H40ClNO11 |
Cas No. | 2055013-68-6 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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