aminooxy-peg8-acid

Aminooxy-PEG8-acid is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands critical for PROTAC molecule formation, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Cbz-aminooxy-PEG8-acid is a PEG-based linker used in PROTACs to join two essential ligands, facilitating selective protein degradation through the ubiquitin-proteasome system within cells.

Fmoc-8-amino-3,6-dioxaoctanoic acid (Fmoc-NH-PEG2-CH2COOH) is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) and a PEG-based PROTAC linker for the synthesis of PROTACs.

Aminooxy-PEG3-acid is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Fmoc-aminooxy-PEG4-acid is a PEG-based linker compound used in PROTAC synthesis [1].

Aminooxy-PEG4-acid, a PEG-based linker for PROTACs, joins two essential ligands critical for forming PROTAC molecules and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-Aminooxy (MW 2000) is a polyethylene glycol (PEG) derived PROTAC linker, primarily used for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs. N-Fmoc-8-aminooctanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Fmoc-aminooxy-PEG12-acid, a PEG-based PROTAC linker, is employed for synthesizing PROTACs[1].

Boc-Aminooxy-PEG3-acid, a PEG-based linker for PROTACs, connects two essential ligands critical for forming PROTAC molecules, thus facilitating selective protein degradation by utilizing the ubiquitin-proteasome system within cells.

t-Boc-Aminooxy-PEG12-acid is a polyethylene glycol (PEG)-based PROTAC linker used for synthesizing PROTACs [1].

Aminooxy-PEG-OH (MW 2000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs[1].