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Amlitelimab

🥰Excellent
Catalog No. T78299
Alias SAR445229, SAR 445229, KY1005, KY 1005

Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis.

Amlitelimab

Amlitelimab

🥰Excellent
Catalog No. T78299Alias SAR445229, SAR 445229, KY1005, KY 1005
Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis.
Pack SizePriceAvailabilityQuantity
1 mg$197In Stock
5 mg$516In Stock
10 mg$828In Stock
25 mg$1,230In Stock
50 mg$1,650In Stock
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Concentration:5.67 mg/mL
Purity:>95%
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Product Introduction

Bioactivity
Description
Amlitelimab (KY1005) is a monoclonal antibody targeting OX40 ligand (OX40L), inhibiting KLH-driven immune responses, used in the study of atopic dermatitis.
In vitro
Amlitelimab (150 μg/mL) effectively inhibits the proliferation of human CD3 T cells [3].
In vivo
In non-human primate graft-versus-host disease (GVHD) models, treatment with Amlitelimab (10mg/kg) showed significant biological activity (extending median GVHD free survival from 8 days to 19.5 days). [1]
AliasSAR445229, SAR 445229, KY1005, KY 1005
Chemical Properties
Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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