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Antifungal agent 22

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Catalog No. T62658Cas No. 2640054-39-1

Antifungal agent 22 (compound D16) is an orally active antifungal agent with an IC50 of 0.5 μg/mL, exhibiting blood-brain barrier permeability, good metabolic stability, and low cytotoxicity. It selectively targets C. neoformans H99 cells by disrupting the integrity of the fungal cell membrane.

Antifungal agent 22

Antifungal agent 22

😃Good
Catalog No. T62658Cas No. 2640054-39-1
Antifungal agent 22 (compound D16) is an orally active antifungal agent with an IC50 of 0.5 μg/mL, exhibiting blood-brain barrier permeability, good metabolic stability, and low cytotoxicity. It selectively targets C. neoformans H99 cells by disrupting the integrity of the fungal cell membrane.
Pack SizePriceAvailabilityQuantity
25 mg$2,1406-8 weeks
50 mg$2,7856-8 weeks
100 mg$3,5206-8 weeks
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Product Introduction

Bioactivity
Description
Antifungal agent 22 (compound D16) is an orally active antifungal agent with an IC50 of 0.5 μg/mL, exhibiting blood-brain barrier permeability, good metabolic stability, and low cytotoxicity. It selectively targets C. neoformans H99 cells by disrupting the integrity of the fungal cell membrane.
Chemical Properties
Molecular Weight446.86
FormulaC21H26Cl3NOS
Cas No.2640054-39-1
Storage & Solubility Information
StorageShipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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