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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $139 | 7-10 days | |
5 mg | $413 | 7-10 days | |
10 mg | $689 | 7-10 days | |
25 mg | $1,490 | 7-10 days | |
50 mg | $2,380 | 7-10 days | |
100 mg | $3,790 | 7-10 days |
Description | AS-85, a potent inhibitor of ASH1L histone methyltransferase (IC50 = 0.6 μM), exhibits anti-leukemic activity by strongly binding to the ASH1L SET domain (Kd = 0.78 μM). |
In vitro | AS-85 inhibits the growth of leukemia cells (MV4;11, MOLM13, and KOPN8) with various MLL1 translocations, showing GI50 values of 5-25 μM, and demonstrates no effect on K562 leukemia cells without MLL1 translocations[1]. |
Molecular Weight | 579.66 |
Formula | C26H28F3N5O3S2 |
Cas No. | 2323623-80-7 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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