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AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | $223 | 2-4 weeks | |
10 mg | $398 | 2-4 weeks | |
50 mg | $1,190 | 2-4 weeks | |
100 mg | $1,850 | 2-4 weeks | |
200 mg | Inquiry | 2-4 weeks | |
500 mg | Inquiry | 2-4 weeks |
Description | AT-1002 TFA is a tight junction regulator and absorption enhancer. It is a 6-mer synthetic peptide. |
In vitro | AT-1002 reversibly increases the paracellular transport of molecules across the epithelial barrier. AT-1002 can undergo Cys-Cys dimerization [1]. Undifferentiated Caco-2 cells are treated with AT-1002 (0 to 5 mg/mL, 3 or 24 hours) and viability is assessed by measuring cellular ATP content. Treatment with AT-1002 for up to 3 h does not affect cell viability at any concentration. In particular, the viability of Caco-2 cells is not affected by 5 mg/mL AT-1002. AT-1002 reduces cell viability after 24 h at concentrations of 2.5 mg/mL and higher. However, the cells remain viable after 24 h if the cells are washed after exposure to AT-1002 for 3 h [2]. |
Alias | AT-1002 TFA |
Molecular Weight | 821.91 |
Formula | C34H54F3N9O9S |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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