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Azido-PEG8-Boc is a polyethylene glycol (PEG) and alkyl/ether-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
Description | Azido-PEG8-Boc is a polyethylene glycol (PEG) and alkyl/ether-based linker used in the synthesis of proteolysis-targeting chimeras (PROTACs)[1]. |
In vitro | PROTACs consist of two distinct ligands linked together: one targets an E3 ubiquitin ligase, and the other targets the desired protein, leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Molecular Weight | 523.62 |
Formula | C23H45N3O10 |
Cas No. | 1623791-99-0 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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