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Becampanel
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Catalog No. T14281Cas No. 188696-80-2
Alias AMP 397
Becampanel (AMP397) is the first competitive AMPA antagonist and functions as an antiepileptic agent.
Becampanel
😃Good
Catalog No. T14281Alias AMP 397Cas No. 188696-80-2
Becampanel (AMP397) is the first competitive AMPA antagonist and functions as an antiepileptic agent.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | 1.444 € | 6-8 weeks | |
| 50 mg | 1.881 € | 6-8 weeks | |
| 100 mg | 2.375 € | 6-8 weeks |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Becampanel (AMP397) is the first competitive AMPA antagonist and functions as an antiepileptic agent. |
| In vitro | Becampanel showed no activity in the mouse lymphoma tk assay without metabolic activation (S9) after a 24-hour treatment. However, it weakly induced micronuclei formation at the highest tested concentrations in V79 cells when metabolic activation (S9) was present[1]. |
| In vivo | Becampanel demonstrated no genotoxic potential in vivo, evidenced by its negative results in studies including those at maximum tolerated doses of 320 mg/kg in mice and 2000 mg/kg in rats[1]. |
| Alias | AMP 397 |
| Molecular Weight | 330.19 |
| Formula | C10H11N4O7P |
| Cas No. | 188696-80-2 |
| Relative Density. | 1.702g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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