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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Benzyl-N-bis(PEG3-Boc) is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands necessary for PROTAC formation, thereby enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, composed of two ligands connected by a linker—one targeting an E3 ubiquitin ligase and the other the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | N-Benzyl-N-bis(PEG3-t-butyl ester) |
Molecular Weight | 627.81 |
Formula | C33H57NO10 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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