Shopping Cart
- Remove All
Your shopping cart is currently empty
BIBS 39
😃Good
Catalog No. T3178Cas No. 133085-33-3
BIBS 39 is a novel nonpeptide angiotensin II (AII) receptor antagonist.
BIBS 39
😃Good
Catalog No. T3178Cas No. 133085-33-3
BIBS 39 is a novel nonpeptide angiotensin II (AII) receptor antagonist.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $36 | In Stock | |
| 2 mg | $51 | In Stock | |
| 5 mg | $79 | In Stock | |
| 10 mg | $122 | In Stock | |
| 25 mg | $198 | In Stock | |
| 50 mg | $278 | Backorder | |
| 1 mL x 10 mM (in DMSO) | $92 | In Stock |
Bulk & Custom
Add to Cart
Questions
View MoreInhibitors Related to "BIBS 39"
Azilsartan
Cited
TAK-536
T1057147403-03-0
Azilsartan (TAK-536) is an Angiotensin 2 Receptor Blocker that acts as an Angiotensin 2 Type 1 Receptor Antagonist, leading to a physiologic effect of decreased blood pressure.
- $30
Size
QTY
CitedLosartan Cited
DuP-753
T0215L114798-26-4
Losartan (DuP-753) is an angiotensin II receptor antagonist.
- $50
Size
QTY
CitedSacubitril/Valsartan
Valsartan, Sacubitril mixture with Valsartan, Sacubitril, LCZ696
T2318936623-90-4
Sacubitril/Valsartan (LCZ696) is an orally bioavailable, dual angiotensin II receptor and neprilysin inhibitor for the treatment of hypertension and heart failure.
- $38
Size
QTY
Captopril Cited
SQ-14534, SQ 14225, SA333
T146262571-86-2
Captopril (SA333) is a potent and specific inhibitor of peptidyl-dipeptidase A. It blocks the conversion of angiotensin I to angiotensin II, a vasoconstrictor and important regulator of arterial blood pressure.
- $40
Size
QTY
CitedIrbesartan
SR-47436, BMS-186295
T1615138402-11-6
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker whose mechanism of action involves antagonizing the Angiotensin 2 Receptor.
- $48
Size
QTY
Ramipril
Tritace, HOE-498, Carasel, Altace
T164587333-19-5
Ramipril (Altace) is a long-acting angiotensin-converting enzyme inhibitor. It is a prodrug that is transformed in the liver to its active metabolite ramiprilat.
- $40
Size
QTY
Enalapril Maleate
Vasotec Maleate, Renitec Maleate, MK-421 Maleate, MK-421 (maleate), Glioten Maleate
T648676095-16-4
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.
- $42
Size
QTY
Tranilast Cited
SB 252218, MK 341
T269053902-12-8
Tranilast (SB 252218), an antiallergic drug, suppresses lipid mediator and cytokine release from inflammatory cells, therefore utilized in the treatment of allergic disorders.
- $36
Size
QTY
CitedLosartan potassium
MK 954, DuP-753 potassium, DuP 753
T0215124750-99-8
Losartan potassium (DuP-753 potassium), an Angiotensin II Receptor Blocker, selectively and competitively inhibits the binding of angiotensin II to the angiotensin I (AT1) receptor.
- $33
Size
QTY
Olmesartan Medoxomil
CS 866, Benicar
T1518144689-63-4
Olmesartan Medoxomil (Benicar) is an angiotensin II type 1 receptor blocker that is used to manage hypertension.
- $30
Size
QTY
Azilsartan Methyl Ester
T66580147403-52-9
Azilsartan Methyl Ester is an angiotensin II receptor antagonist. Azilsartan Methyl Ester inhibits specific binding of [125I]AII (0.2 nM) to bovine adrenal cortex with IC50 value is 0.44uM.
- $37
Size
QTY
Valsartan Methyl Ester
T67848137863-17-3
Valsartan Methyl Ester is a potent angiotensin II receptor antagonist, IC50= 0.06uM.
- $38
Size
QTY
Select Batch
Contact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | BIBS 39 is a novel nonpeptide angiotensin II (AII) receptor antagonist. |
| Targets&IC50 | AT1 receptor:29 ± 7 nM (ki), AT2 receptor:480 ± 110 nM (ki) |
| Molecular Weight | 524.65 |
| Formula | C32H36N4O3 |
| Cas No. | 133085-33-3 |
| Smiles | CCCCc1nc2ccc(NC(=O)NC3CCCCC3)cc2n1Cc1ccc(cc1)-c1ccccc1C(O)=O |
| Relative Density. | 1.24g/cm3 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 32 mg/mL (60.99 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
DMSO
| |||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy BIBS 39 | purchase BIBS 39 | BIBS 39 cost | order BIBS 39 | BIBS 39 chemical structure | BIBS 39 formula | BIBS 39 molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.