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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Bis-PEG11-acid is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs are composed of two distinct ligands linked together: one ligand targets an E3 ubiquitin ligase, and the other targets the desired protein. They utilize the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1]. |
Molecular Weight | 602.67 |
Formula | C26H50O15 |
Cas No. | 2097010-30-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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