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Bis-PEG25-TFP ester, a PEG-based linker for PROTACs, connects two essential ligands necessary for the formation of PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Bis-PEG25-TFP ester, a PEG-based linker for PROTACs, connects two essential ligands necessary for the formation of PROTAC molecules, facilitating selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands linked together: one binding to an E3 ubiquitin ligase and the other to the target protein, utilizing the intracellular ubiquitin-proteasome system for selective protein degradation [1]. |
Molecular Weight | 1515.52 |
Formula | C66H106F8O29 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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