Shopping Cart
- Remove All
- Your shopping cart is currently empty
Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $155 | 35 days | |
10 mg | $1,190 | 35 days |
Description | Motixafortide (BKT140 4-fluorobenzoyl) is an antagonist of CXCR4 (IC50: 1 nM). BMS-1166 hydrochloride is an inhibitor of PD-1/PD-L1 interaction (IC50: 1.4 nM). BMS-1166 rivalries the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation. |
Targets&IC50 | PD-1/PD-L1:1.4 nM |
In vitro | BMS-1166 is a potent inhibitor of PD-1/PD-L1 interaction, showing an IC50 of 1.4 nM in a homogenous time-resolved fluorescence binding assay[1] and dose-dependently abolishing the inhibition of ECs stimulation by sPD-L1[2]. |
Molecular Weight | 677.57 |
Formula | C36H34Cl2N2O7 |
Cas No. | 2113650-05-6 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.