Shopping Cart

Remove All
Your shopping cart is currently empty

Boc-C1-PEG2-C4-Cl

Name: Boc-C1-PEG2-C4-Cl
Brand: TargetMol
SKU: T18637
Price: 41 USD
Availability: InStock
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T18637Cas No. 1835705-53-7

Alias PROTAC Linker 1

Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based compound used as a linker in the synthesis and development of PROTACs[1].

Boc-C1-PEG2-C4-Cl

🥰Excellent

Catalog No. T18637Alias PROTAC Linker 1Cas No. 1835705-53-7

Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based compound used as a linker in the synthesis and development of PROTACs[1].

Product information is being updated, if you want to purchase, please click the bulk custom button.

Bulk & Custom

Questions

Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based compound used as a linker in the synthesis and development of PROTACs[1].
In vitro	PROTAC technology utilizes small molecules to facilitate the ubiquitination and subsequent proteasomal degradation of target proteins. This report details the creation of PROTAC compounds designed for the degradation of c-ABL and BCR-ABL proteins by harnessing Cereblon or Von Hippel Lindau E3 ligases. The molecule Boc-C1-PEG2-C4-Cl is identified as 6-2-2[1].
Alias	PROTAC Linker 1

Chemical Properties

Molecular Weight	294.82
Formula	C₁₄H₂₇ClO₄
Cas No.	1835705-53-7
Relative Density.	1.026 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (169.60 mM)

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3919 mL	16.9595 mL	33.9190 mL	169.5950 mL
5 mM	0.6784 mL	3.3919 mL	6.7838 mL	33.9190 mL
10 mM	0.3392 mL	1.6960 mL	3.3919 mL	16.9595 mL
20 mM	0.1696 mL	0.8480 mL	1.6960 mL	8.4798 mL
50 mM	0.0678 mL	0.3392 mL	0.6784 mL	3.3919 mL
100 mM	0.0339 mL	0.1696 mL	0.3392 mL	1.6960 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Boc C1 PEG2 C4 ClBoc-C1-PEG2-C4-ClBocC1PEG2C4ClBoc-C-1-PEG2-C4-Cl