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BOLD-100 free base

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Catalog No. T72543Cas No. 783324-98-1
Alias NKP-1339 free base ; IT-139 free base ; KP-1339 free base, NKP-1339 free base, KP-1339 free base, IT-139 free base

BOLD-100 free base (NKP-1339; IT-139), a ruthenium-based anticancer agent, inhibits stress-induced GRP78 upregulation, thus disrupting endoplasmic reticulum (ER) homeostasis. This action induces ER stress and unfolded protein response (UPR), interfering with the intricate relationship between ER-stress response, lysosome dynamics, and autophagy execution.

BOLD-100 free base
Other Forms of BOLD-100 free base:
NKP-1339TQ0016197723-00-5
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BOLD-100 free base

😃Good
Catalog No. T72543Alias NKP-1339 free base ; IT-139 free base ; KP-1339 free base, NKP-1339 free base, KP-1339 free base, IT-139 free baseCas No. 783324-98-1
BOLD-100 free base (NKP-1339; IT-139), a ruthenium-based anticancer agent, inhibits stress-induced GRP78 upregulation, thus disrupting endoplasmic reticulum (ER) homeostasis. This action induces ER stress and unfolded protein response (UPR), interfering with the intricate relationship between ER-stress response, lysosome dynamics, and autophagy execution.
Pack SizePriceAvailabilityQuantity
5 mg$332Backorder
50 mg$1,820Backorder
100 mg$2,500Backorder
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Product Introduction

Bioactivity
Description
BOLD-100 free base (NKP-1339; IT-139), a ruthenium-based anticancer agent, inhibits stress-induced GRP78 upregulation, thus disrupting endoplasmic reticulum (ER) homeostasis. This action induces ER stress and unfolded protein response (UPR), interfering with the intricate relationship between ER-stress response, lysosome dynamics, and autophagy execution.
AliasNKP-1339 free base ; IT-139 free base ; KP-1339 free base, NKP-1339 free base, KP-1339 free base, IT-139 free base
Chemical Properties
Molecular Weight479.15
FormulaC14H12Cl4N4Ru
Cas No.783324-98-1
Storage & Solubility Information
StorageShipping with blue ice.

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Keywords

BOLD-100KP1339IT-139NKP-1339 free base ; IT-139 free base ; KP-1339BOLD-100 free baseIT139NKP-1339 free base ; IT-139 free base ; KP1339NKP-1339 free base ; IT-139 free base ; KP 1339KP-1339BOLD100NKP-1339IT 139BOLD 100KP 1339NKP1339NKP 1339
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