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NKP-1339

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Catalog No. TQ0016Cas No. 197723-00-5
Alias KP-1339, IT-139

NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.

NKP-1339

NKP-1339

😃Good
Catalog No. TQ0016Alias KP-1339, IT-139Cas No. 197723-00-5
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
Pack SizePriceAvailabilityQuantity
2 mg188 €5 days
5 mg329 €5 days
25 mg1.083 €6-8 weeks
50 mg1.415 €6-8 weeks
100 mg1.890 €6-8 weeks
1 mL x 10 mM (in DMSO)363 €5 days
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Product Introduction

Bioactivity
Description
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
In vitro
NKP-1339 can strongly bind to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu.
AliasKP-1339, IT-139
Chemical Properties
Molecular Weight502.14
FormulaC14H12Cl4N4NaRu
Cas No.197723-00-5
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 55 mg/mL (109.53 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.9915 mL9.9574 mL19.9148 mL99.5738 mL
5 mM0.3983 mL1.9915 mL3.9830 mL19.9148 mL
10 mM0.1991 mL0.9957 mL1.9915 mL9.9574 mL
20 mM0.0996 mL0.4979 mL0.9957 mL4.9787 mL
50 mM0.0398 mL0.1991 mL0.3983 mL1.9915 mL
100 mM0.0199 mL0.0996 mL0.1991 mL0.9957 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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