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NKP-1339
Catalog No. TQ0016Cas No. 197723-00-5
Alias KP-1339, IT-139
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
NKP-1339
Catalog No. TQ0016Alias KP-1339, IT-139Cas No. 197723-00-5
NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 2 mg | $198 | 5 days | |
| 5 mg | $347 | 5 days | |
| 25 mg | $1,140 | 6-8 weeks | |
| 50 mg | $1,490 | 6-8 weeks | |
| 100 mg | $1,990 | 6-8 weeks | |
| 1 mL x 10 mM (in DMSO) | $383 | 5 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. |
| In vitro | NKP-1339 can strongly bind to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu. |
| Alias | KP-1339, IT-139 |
| Molecular Weight | 502.14 |
| Formula | C14H12Cl4N4NaRu |
| Cas No. | 197723-00-5 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 55 mg/mL (109.53 mM) | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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